Results from the surgical resection of severe heterotopic ossification of the hip: a case series of 26 patients

Eur J Orthop Surg Traumatol. 2017 Dec;27(8):1097-1102. doi: 10.1007/s00590-017-1980-2. Epub 2017 Jun 6.

Abstract

Introduction: Surgical resection of heterotopic ossification (HO) around the hip joint is often challenging. The aim of this study is to evaluate the clinical and radiological outcomes following surgical resection of Brooker's type III and IV HO of the hip.

Methods: We retrospectively reviewed clinical and radiological data, between November 2006 and January 2013, of all patients who underwent surgical resection of severe HO of the hip. Brooker's grading, range of motion and the Harris Hip Score before and after surgery were recorded in all cases. The combined radiation (700 cGy preoperatively) and indomethacin regimen was used to prevent heterotopic ossification recurrence.

Results: Twenty-six patients (22 males and 4 females) were included in our study. Mean patient age was 47.38 years (range 24-72). The HO was graded as Brooker grade III in 3 patients (11.5%) and Brooker grade IV in 23 patients (88.5%). Mean time interval between HO development and resection was 40.8 months (range 13-156 months). All patients had CT scans prior to surgery. Mean follow-up was 31.4 months (range 24-40 months). There was no severe HO recurrence. Complications included one intraoperative injury of a femoral artery branch, one intraoperative femoral neck fracture treated with intramedullary nailing, one sciatic nerve injury and one superficial infection treated conservatively.

Conclusions: Surgical resection of severe HO of the hip along with preoperative radiation and indomethacin provides excellent results; however, the complication rate is relatively high. Careful evaluation of the preoperative CT scan and wide exposure are required in order to identify all the involved neurovascular structures.

Keywords: Brooker classification; Heterotopic ossification; Surgical resection.

MeSH terms

  • Adult
  • Aged
  • Combined Modality Therapy
  • Cyclooxygenase Inhibitors / therapeutic use
  • Female
  • Follow-Up Studies
  • Hip Joint / diagnostic imaging
  • Hip Joint / surgery*
  • Humans
  • Indomethacin / therapeutic use
  • Intraoperative Complications / etiology
  • Male
  • Middle Aged
  • Ossification, Heterotopic / diagnostic imaging
  • Ossification, Heterotopic / surgery*
  • Ossification, Heterotopic / therapy
  • Preoperative Period
  • Radiotherapy
  • Range of Motion, Articular
  • Retrospective Studies
  • Secondary Prevention
  • Treatment Outcome
  • Young Adult

Substances

  • Cyclooxygenase Inhibitors
  • Indomethacin