Short- and long-term outcomes of the Frey procedure for chronic pancreatitis: a single-center experience and summary of outcomes in Japan

Surg Today. 2018 Jan;48(1):58-65. doi: 10.1007/s00595-017-1548-0. Epub 2017 Jun 8.

Abstract

Purpose: To evaluate the short- and long-term outcomes of the Frey procedure for chronic pancreatitis (CP).

Methods: The subjects of this study were 12 patients who underwent the Frey procedure for CP between January, 2000 and December, 2016. We assessed pain relief, weight gain, and exocrine/endocrine insufficiency during follow-up.

Results: The study population comprised 11 men and 1 woman (91.7% vs. 8.3%; mean age, 50.3 ± 6.8 years; range 39-61 years). Pancreatitis was caused by alcohol in 9 (75%) patients and was idiopathic in 3 (25%) patients. The mean follow-up period was 82.5 ± 46.5 months (range 16.9-152.1 months). There was no operative mortality, but three patients (25%) suffered postoperative morbidity. All patients were pain-free at the time of discharge. There was no case of new-onset diabetes mellitus after surgery, although one patient (8.3%) suffered exocrine insufficiency. The body weight and body mass index of all patients improved during follow-up. Only one patient continued to suffer pain in the long term.

Conclusion: The findings of this long-term follow-up of patients who underwent the Frey procedure suggest that it offers effective pain relief and is a safe technique for the management of CP.

Keywords: Chronic pancreatitis; Frey; Long-term follow-up; Pain; Surgery.

MeSH terms

  • Adult
  • Body Mass Index
  • Female
  • Follow-Up Studies
  • Humans
  • Japan
  • Male
  • Middle Aged
  • Pancreatectomy / methods*
  • Pancreaticojejunostomy / methods*
  • Pancreatitis, Chronic / diagnostic imaging
  • Pancreatitis, Chronic / surgery*
  • Retrospective Studies
  • Time Factors
  • Treatment Outcome