Intrathoracic rupture of hydatid cyst of the liver is a rare but severe complication of echinococcal disease. It represent a serious condition responsible for lesions at 3 levels: hepatic, diaphragmatic, and pulmonary. Early diagnosis and management of septic associated complications are essential. We present the case of a 55 year old female patient with a giant hydatid cyst type CE 2 based on WHO Classification, communicating with the biliary tree and with a massive extension to the right hemithorax.