Renal cysts occur in approximately 50% of patients with tuberous sclerosis complex, but their clinical significance and response to treatment are unknown. Abdominal imaging of 15 patients with tuberous sclerosis complex-associated renal cystic disease who had received mammalian target of rapamycin inhibitor therapy for other tuberous sclerosis complex-related indications was evaluated. Reductions in cyst number, sum diameter, and volume were observed.
Keywords: autosomal dominant polycystic kidney disease; case series; contiguous gene syndrome; subependymal giant cell astrocytoma; tuberous sclerosis complex.
Copyright © 2017 Elsevier Inc. All rights reserved.