Recommendations for the clinical practice of Nice-Saint-Paul de Vence The treatment of advanced epithelial ovarian cancer is multidisciplinary involving surgical teams and surgery and medical oncology, experienced in the management of this disease, following published quality criteria. The strategy must be validated in multidisciplinary consultation meeting (RCP) before any treatment. The pre-therapeutic assessment includes the histological diagnosis, evaluation of the tumor extension (biological assessment, markers, imaging, laparoscopy), assessment of the general state (operability), in order to answer the question of feasibility of an initial optimal surgery. The standard treatment involves complete surgical resections of the lesions by median laparotomy, followed by adjuvant chemotherapy based on carboplatin and paclitaxel, six cycles with the possibility of treatment with bevacizumab during adjuvant treatment and in maintenance. If complete surgery is not feasible as a result of the initial assessment, interval debulking surgery is considered after 3 to 4 courses of induction chemotherapy.
Keywords: Cancer de l’ovaire; First line; Multidisciplinarity; Ovarian cancer; Pluridisciplinarité; Prise en charge initiale.
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