11C-Choline positive but 18F-FDG negative pancreatic metastasis from renal cell carcinoma on PET

Nagoya J Med Sci. 2017 Feb;79(2):273-277. doi: 10.18999/nagjms.79.2.273.

Abstract

Choline is a new PET tracer, which uptake may occur via a choline-specific transporter protein and be accelerated during the proliferation of tumor cells. We report a 61-year-old woman with a metastatic pancreatic tumor from renal cell carcinoma, measuring 35×40 mm. PET scans demonstrated accumulation of 11C-choline in the metastatic pancreatic tumor, but no accumulation of 18F-FDG. Choline PET/CT may play a useful and complementary imaging modality, especially when FDG-PET/CT does not show expected findings or when the evaluation of tumor viability is needed, in patients with renal cell carcinoma.

Keywords: Choline; FDG; PET; Renal cell carcinoma.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Renal Cell / complications
  • Carcinoma, Renal Cell / drug therapy*
  • Choline / chemistry*
  • Female
  • Fluorodeoxyglucose F18 / analysis*
  • Humans
  • Kidney Neoplasms / complications
  • Kidney Neoplasms / drug therapy*
  • Middle Aged
  • Positron Emission Tomography Computed Tomography / methods*

Substances

  • Fluorodeoxyglucose F18
  • Choline