Clinical characteristics of type A acute aortic dissection with CNS symptom

Am J Emerg Med. 2017 Dec;35(12):1836-1838. doi: 10.1016/j.ajem.2017.06.011. Epub 2017 Jun 6.

Abstract

Background and purpose: Accurate diagnosis of acute aortic dissection (AAD) is sometimes difficult because of accompanying central nervous system (CNS) symptoms. The purpose of this study was to investigate the clinical characteristics of Type A AAD (TAAAD) with CNS symptoms.

Methods: We retrospectively reviewed the medical records of 8403 patients ambulanced to our emergency and critical care center between April 2009 and May 2014.

Results: We identified 59 TAAAD patients for the analysis (mean age, 67.3±10.5years; 37 (62.0%) male). Eleven patients (18.6%) presented CNS symptoms at the onset of TAAAD, and these patients complained less frequently of typical chest and back pain than those without CNS symptoms (p<0.0001). Initial systolic and diastolic blood pressure were lower (p=0.003, and p=0.049, respectively) and involvement of the supra-aortic artery was more frequent in patients with CNS symptoms (p<0.0001).

Conclusion: Because CNS symptom can mask chest and back pain caused by TAAAD, physicians should always consider the possibility of TAAAD in patients with CNS symptoms in emergency medicine settings.

Keywords: Acute aortic dissection; Carotid ultrasonography; Painless.

MeSH terms

  • Aged
  • Aortic Aneurysm, Thoracic / diagnostic imaging*
  • Aortic Aneurysm, Thoracic / epidemiology
  • Aortic Aneurysm, Thoracic / physiopathology
  • Aortic Dissection / diagnostic imaging*
  • Aortic Dissection / epidemiology
  • Aortic Dissection / physiopathology
  • Blood Pressure
  • Central Nervous System Diseases / complications
  • Central Nervous System Diseases / diagnostic imaging*
  • Central Nervous System Diseases / physiopathology
  • Contrast Media
  • Emergency Service, Hospital*
  • Female
  • Humans
  • Japan / epidemiology
  • Male
  • Retrospective Studies
  • Tomography, X-Ray Computed*

Substances

  • Contrast Media