IFNɣ Block, Treosulfan Conditioning and αβ T Cell Deplete PBSCT for XIAP-Deficient HLH

J Clin Immunol. 2017 Aug;37(6):511-513. doi: 10.1007/s10875-017-0413-7. Epub 2017 Jun 21.

Authors

Ciara O'Rafferty¹, Mark Velangi², Sarah Lawson², Prashant Hiwarkar², Jayashree Motwani²

Affiliations

¹ Department of Haematology, Birmingham Children's Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK. [email protected].
² Department of Haematology, Birmingham Children's Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK.

PMID: 28639166
DOI: 10.1007/s10875-017-0413-7

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Antibodies, Blocking / therapeutic use*
Antibodies, Monoclonal / therapeutic use*
Antigens, CD19 / metabolism
Busulfan / analogs & derivatives*
Busulfan / therapeutic use
Chimerism
Genetic Diseases, X-Linked / genetics
Genetic Diseases, X-Linked / therapy*
Humans
Infant
Infant, Newborn
Interferon-gamma / immunology
Lymphocyte Depletion
Lymphoproliferative Disorders / genetics
Lymphoproliferative Disorders / therapy*
Male
Peripheral Blood Stem Cell Transplantation*
Receptors, Antigen, T-Cell, alpha-beta / metabolism
T-Lymphocytes / immunology*
Transplantation Conditioning
X-Linked Inhibitor of Apoptosis Protein / genetics*

Substances

Antibodies, Blocking
Antibodies, Monoclonal
Antigens, CD19
Receptors, Antigen, T-Cell, alpha-beta
X-Linked Inhibitor of Apoptosis Protein
XIAP protein, human
Interferon-gamma
treosulfan
Busulfan

Supplementary concepts

Lymphoproliferative Syndrome, X-Linked, 2