Investigation of pre-XDR Beijing Mycobacterium tuberculosis transmission to a healthcare worker in France, 2016

J Hosp Infect. 2017 Dec;97(4):414-417. doi: 10.1016/j.jhin.2017.06.030. Epub 2017 Jun 30.

Abstract

A case of occupational contamination of a healthcare worker by a pre-extensively drug-resistant (pre-XDR) Beijing strain of Mycobacterium tuberculosis at the University Hospital of Montpellier, France is reported. The index case was identified using genetic fingerprinting of isolates. This report underscores the risk of healthcare-associated contamination by pre-XDR tuberculosis (TB) in low-incidence countries and the importance of molecular tools for TB care. It also calls for increased vigilance in the management of multi-drug-resistant/XDR TB patients.

Keywords: Beijing; Drug resistance; Molecular epidemiology; Tuberculosis.

Publication types

  • Case Reports

MeSH terms

  • DNA Fingerprinting
  • France
  • Genotype
  • Health Personnel*
  • Humans
  • Molecular Typing
  • Mycobacterium tuberculosis / classification*
  • Mycobacterium tuberculosis / genetics
  • Mycobacterium tuberculosis / isolation & purification*
  • Occupational Exposure*
  • Tuberculosis, Multidrug-Resistant / microbiology*
  • Tuberculosis, Multidrug-Resistant / transmission*