Poorly differentiated vaginal adenocarcinoma with aggressive behavior-Pap smear findings

Diagn Cytopathol. 2017 Nov;45(11):1055-1056. doi: 10.1002/dc.23774. Epub 2017 Jul 3.

Abstract

Vaginal carcinoma is a rare condition. In this report, we describe a case of a poorly differentiated aggressive adenocarcinoma in a woman with a three month history of vaginal bleeding and a negative Pap smear done six months prior to her consultation. Specular examination showed a normal cervix, but there was a bleeding ulcer (2 cm in diameter) in the upper third of the vagina. Cytology revealed poorly differentiated atypical cells, and the biopsy established a diagnosis of vaginal adenocarcinoma with little differentiation. Within two months, the patient died without diagnosis of a primary tumor site other than the vagina.

Keywords: adenocarcinoma; cancer; ulcer; vagina.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / pathology*
  • Adult
  • Female
  • Humans
  • Papanicolaou Test
  • Vaginal Neoplasms / pathology*
  • Vaginal Smears