A case of penta X syndrome caused by nondisjunction in maternal meiosis 1 and 2

Clin Case Rep. 2017 Jun 1;5(7):1136-1140. doi: 10.1002/ccr3.1004. eCollection 2017 Jul.

Abstract

The prenatal abnormalities in patients with penta X syndrome appear late in pregnancy and are nonspecific. In contrast, the postnatal phenotype is well described although new findings are still revealed. Penta X syndrome is a result of successive nondisjunctions of the X chromosomes in both maternal meiotic divisions.

Keywords: Dilated intestines; Penta X syndrome; Pentasomy X; STR marker; genotyping; hypoplasia of the corpus callosum; microarray; nondisjunction; short femora.

Publication types

  • Case Reports