Multiparametric magnetic resonance imaging for transition zone prostate cancer: essential findings, limitations, and future directions

Sara Lewis; Cecilia Besa; Ally Rosen; Ardeshir R Rastinehad; Sahar Semaan; Stefanie Hectors; Bachir Taouli

doi:10.1007/s00261-017-1184-6

Multiparametric magnetic resonance imaging for transition zone prostate cancer: essential findings, limitations, and future directions

Abdom Radiol (NY). 2017 Nov;42(11):2732-2744. doi: 10.1007/s00261-017-1184-6.

Authors

Sara Lewis^{1

2}, Cecilia Besa³, Ally Rosen⁴, Ardeshir R Rastinehad⁵, Sahar Semaan^{4

3}, Stefanie Hectors³, Bachir Taouli^{4

3}

Affiliations

¹ Department of Radiology, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY, 10029, USA. [email protected].
² Translational and Molecular Imaging Institute (TMII), Icahn School of Medicine at Mount Sinai, New York, NY, USA. [email protected].
³ Translational and Molecular Imaging Institute (TMII), Icahn School of Medicine at Mount Sinai, New York, NY, USA.
⁴ Department of Radiology, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY, 10029, USA.
⁵ Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

PMID: 28702787
DOI: 10.1007/s00261-017-1184-6

Abstract

Objective: Review the multiparametric MRI (mpMRI) findings of transition zone (TZ) prostate cancer (PCa) using T2-weighted imaging (T2WI), diffusion-weighted imaging (DWI), and dynamic contrast-enhanced (DCE) MRI and to integrate mpMRI findings with clinical history, laboratory values, and histopathology.

Conclusion: TZ prostate tumors are challenging to detect clinically and at MRI. mpMRI using the combination of sequences has the potential to improve accuracy of TZ cancer detection and staging.

Keywords: Benign prostatic hypertrophy (BPH); Multiparametric magnetic resonance imaging (mpMRI); Prostate cancer; Transition zone.

Publication types

Review

MeSH terms

Biomarkers, Tumor / analysis
Contrast Media
Humans
Image Enhancement / methods
Magnetic Resonance Imaging / methods*
Male
Prostatic Neoplasms / diagnostic imaging*
Prostatic Neoplasms / pathology

Substances

Biomarkers, Tumor
Contrast Media