Survival of Atherosclerotic Calcifications in Skeletonized Material: Forensic and Pathological Implications

J Forensic Sci. 2018 Mar;63(2):386-394. doi: 10.1111/1556-4029.13592. Epub 2017 Jul 18.

Abstract

Atherosclerosis is a chronic inflammatory disease creating calcifying plaques in the arterial walls. Because its paleopathological diagnosis remains little studied on skeletal remains, its impact on forensic and archeological data is completely underestimated. Here, 24 skeletal remains from the Milano Cemetery Skeletal Collection have been studied to evaluate the chance of atherosclerotic calcification survival, retrieval, and identification. Through direct comparison with a known autopsy collection and literature, the identification and categorization of several types of calcifications were performed. Clothing elements such as tights or socks played a definitive role in the preservation of the calcifications; hence they are more likely to be found in forensic cases than in archeological ones. Therefore, vascular calcifications are possible to collect and identify in skeletal remains if sufficient care is given to their recovery. Consequently and as markers of the disease, such identification can provide valuable pathological information for forensic and archeological cases.

Keywords: arteriosclerosis; atherosclerosis; bone pathology; forensic anthropology; forensic science; physical anthropology; vascular calcifications.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Atherosclerosis / pathology*
  • Case-Control Studies
  • Female
  • Forensic Pathology*
  • Humans
  • Male
  • Middle Aged
  • Plaque, Atherosclerotic / pathology*
  • Tunica Intima / pathology
  • Vascular Calcification / pathology*