Highly fluorescent hyperbranched BODIPY-based conjugated polymer dots for cellular imaging

Chem Commun (Camb). 2017 Jul 27;53(61):8612-8615. doi: 10.1039/c7cc04230b.

Abstract

The first hyperbranched BODIPY-based conjugated polymer dots (Pdots) were reported. The Pdots showed quantum yields of as high as 22%, which is 40% higher than their linear counterparts. The Pdots were successfully applied in cell-labelling applications. These results demonstrated that hyperbranched polymers are a very promising material for biological imaging and applications.

MeSH terms

  • Animals
  • Boron Compounds / chemical synthesis
  • Boron Compounds / chemistry
  • Boron Compounds / pharmacology*
  • Boron Compounds / toxicity
  • Cell Line, Tumor
  • Fluorenes / chemical synthesis
  • Fluorenes / chemistry
  • Fluorenes / pharmacology
  • Fluorenes / toxicity
  • Fluorescence
  • Fluorescent Dyes / chemical synthesis
  • Fluorescent Dyes / chemistry
  • Fluorescent Dyes / pharmacology*
  • Fluorescent Dyes / toxicity
  • Humans
  • Microscopy, Confocal / methods
  • Molecular Structure
  • Polymers / chemical synthesis
  • Polymers / chemistry
  • Polymers / pharmacology*
  • Polymers / toxicity
  • Quantum Dots / chemistry*
  • Quantum Dots / toxicity
  • Streptavidin / chemistry
  • Thiadiazoles / chemical synthesis
  • Thiadiazoles / chemistry
  • Thiadiazoles / pharmacology
  • Thiadiazoles / toxicity
  • Zebrafish

Substances

  • Boron Compounds
  • Fluorenes
  • Fluorescent Dyes
  • Polymers
  • Thiadiazoles
  • Streptavidin