Evaluation of Appropriate Venous Thromboembolism Prophylaxis in Patients With Orthopaedic Trauma With Symptom-Driven Vascular and Radiographic Studies

J Orthop Trauma. 2017 Dec;31(12):611-616. doi: 10.1097/BOT.0000000000000991.

Abstract

Objective: To evaluate venous thromboembolism (VTE) prophylaxis adherence and effectiveness in orthopaedic trauma patients who had vascular or radiographic studies showing deep vein thromboses or pulmonary emboli.

Design: Retrospective review.

Setting: A level I trauma center that independently services a 5-state region.

Patients: Four hundred seventy-six patients with orthopaedic trauma who underwent operative treatments for orthopaedic injuries and had symptom-driven diagnostic VTE studies.

Intervention: The medical records of patients treated surgically between July 2010 and March 2013 were interrogated using a technical tool that electronically captures thrombotic event data from vascular and radiologic imaging studies by natural language processing.

Main outcome measurements: Patients were evaluated for hospital guideline-directed VTE prophylaxis adherence with mechanical or chemical prophylaxis. Patient demographics, associated injuries, mechanism of injury, and symptoms that led to imaging for a VTE were also assessed.

Results: Of the 476 orthopaedic patients who met inclusion criteria, 100 (mean age 52.3 median 52, SD 18.3, 70% men) had positive VTE studies. Three hundred seventy-six (age 47.3, SD 17.3, 69% men) had negative VTE studies. Of the 100 patients with VTE, 63 deep vein thromboses, and 49 pulmonary emboli were found. Eight-five percent of all patients met hospital guideline-VTE prophylaxis standards.

Conclusion: The study population had better than previously reported VTE prophylaxis adherence, however, patients still developed VTEs.

Level of evidence: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Blood Vessels / diagnostic imaging*
  • Female
  • Guideline Adherence
  • Humans
  • Injury Severity Score
  • Male
  • Middle Aged
  • Orthopedic Procedures / adverse effects*
  • Postoperative Complications*
  • Retrospective Studies
  • Tomography, X-Ray Computed / methods*
  • Trauma Centers
  • Ultrasonography, Doppler / methods*
  • Venous Thromboembolism / diagnosis
  • Venous Thromboembolism / etiology
  • Venous Thromboembolism / prevention & control*
  • Wounds and Injuries / complications*
  • Wounds and Injuries / surgery
  • Young Adult