Recent advances in studying single bacteria and biofilm mechanics

Adv Colloid Interface Sci. 2017 Sep:247:573-588. doi: 10.1016/j.cis.2017.07.026. Epub 2017 Jul 21.

Abstract

Bacterial biofilms correspond to surface-associated bacterial communities embedded in hydrogel-like matrix, in which high cell density, reduced diffusion and physico-chemical heterogeneity play a protective role and induce novel behaviors. In this review, we present recent advances on the understanding of how bacterial mechanical properties, from single cell to high-cell density community, determine biofilm tri-dimensional growth and eventual dispersion and we attempt to draw a parallel between these properties and the mechanical properties of other well-studied hydrogels and living systems.

Keywords: Bacteria; Biofilm; Elasticity; Growth; Hydrogel; Mechanics.

Publication types

  • Review

MeSH terms

  • Bacillus subtilis / chemistry*
  • Bacterial Adhesion
  • Biofilms / growth & development*
  • Biomechanical Phenomena
  • Cell Wall / chemistry
  • Escherichia coli / chemistry*
  • Fimbriae, Bacterial / chemistry
  • Hydrogels / chemistry
  • Mechanotransduction, Cellular / physiology*
  • Single-Cell Analysis
  • Staphylococcus aureus / chemistry*
  • Thermodynamics

Substances

  • Hydrogels