MDM4 amplification in a case of de-differentiated liposarcoma and in-silico data supporting an oncogenic event alternative to MDM2 amplification in a subset of cases

Histopathology. 2017 Dec;71(6):1019-1023. doi: 10.1111/his.13331. Epub 2017 Oct 2.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cell Cycle Proteins
  • Gene Amplification
  • Humans
  • Liposarcoma / genetics*
  • Liposarcoma / pathology*
  • Male
  • Neoplasm Recurrence, Local / genetics
  • Neoplasm Recurrence, Local / pathology
  • Nuclear Proteins / genetics*
  • Proto-Oncogene Proteins / genetics*
  • Proto-Oncogene Proteins c-mdm2 / genetics
  • Shoulder / pathology
  • Soft Tissue Neoplasms / genetics*
  • Soft Tissue Neoplasms / pathology*

Substances

  • Cell Cycle Proteins
  • MDM4 protein, human
  • Nuclear Proteins
  • Proto-Oncogene Proteins
  • MDM2 protein, human
  • Proto-Oncogene Proteins c-mdm2