Seven Non-melanoma Features to Rule Out Facial Melanoma

Acta Derm Venereol. 2017 Nov 15;97(10):1219-1224. doi: 10.2340/00015555-2759.

Abstract

Facial melanoma is difficult to diagnose and dermatoscopic features are often subtle. Dermatoscopic non-melanoma patterns may have a comparable diagnostic value. In this pilot study, facial lesions were collected retrospectively, resulting in a case set of 339 melanomas and 308 non-melanomas. Lesions were evaluated for the prevalence (> 50% of lesional surface) of 7 dermatoscopic non-melanoma features: scales, white follicles, erythema/reticular vessels, reticular and/or curved lines/fingerprints, structureless brown colour, sharp demarcation, and classic criteria of seborrhoeic keratosis. Melanomas had a lower number of non-melanoma patterns (p< 0.001). Scoring a lesion suspicious when no prevalent non-melanoma pattern is found resulted in a sensitivity of 88.5% and a specificity of 66.9% for the diagnosis of melanoma. Specificity was higher for solar lentigo (78.8%) and seborrhoeic keratosis (74.3%) and lower for actinic keratosis (61.4%) and lichenoid keratosis (25.6%). Evaluation of prevalent non-melanoma patterns can provide slightly lower sensitivity and higher specificity in detecting facial melanoma compared with already known malignant features.

MeSH terms

  • Algorithms
  • Decision Support Techniques*
  • Dermoscopy*
  • Diagnosis, Differential
  • Facial Neoplasms / epidemiology
  • Facial Neoplasms / pathology*
  • Humans
  • Italy / epidemiology
  • Pilot Projects
  • Predictive Value of Tests
  • Prevalence
  • Retrospective Studies
  • Skin / pathology*
  • Skin Neoplasms / epidemiology
  • Skin Neoplasms / pathology*