Objective: To clarify the research status of economic burden of stomach cancer in China from 1996 to 2015. Methods: Based on three electronic literature databases (China Knowledge Resource Integrated Database, Wanfang Database and PubMed), a total of 2 873, 1 244 and 84 articles published during 1996 to 2015 were found, respectively, using keywords of"cancer","neoplasms","malignant tumor","tumor","economic burden","health expenditure","cost","cost of illness", and"China". According to the inclusion and exclusion criteria, 30 literatures were included in the final analysis. Then the basic information and study subjects, indicators and main results of economic burden were abstracted and analyzed. All the expenditure data were discounted to the values in 2013 by using China's percapita consumer price index. Results: Totally, 30 articles were included, covering 14 provinces and of which 16 were published during 2011-2015. One article was based on population-level and the remaining studies were all based on individual-level. The number of individual-level articles that reported direct medical, non-medical and indirectly economic burden was 29, 1 and 2, respectively. The main indicators of direct medical expenditure were expenditure per patient (22), per clinical visit (9) and per diem (11), respectively. The median expenditure per patient was 7 387-28 743 RMB (CNY), with average annual growth rate (AAGR) of 1.7% (1996-2013). The median expenditure per clinical visit was 18 504-41 871 RMB (2003-2013), with AAGR of 5.5%. The median expenditure per diem was 313-1 445 RMB (1996-2012), with AAGR of 3.7%. Difference was found among provinces. Conclusions: The evidence for economic burden of stomach cancer was still limited over the past two decades and mainly focused on individual and regional levels. An increase and differences in provinces were observed in direct medical expenditure. Evaluation on direct non-medical and indirect medical expenditure needs to be addressed.
目的： 分析中国1996—2015年胃癌经济负担研究现状。 方法： 以"癌"、"癌症"、"恶性肿瘤"、"瘤"、"经济负担"、"费用"、"成本"、"疾病负担"、"中国"、"neoplasms"、"health expenditure"、"cost of illness"、"China"为检索关键词，系统检索中国知网、万方数据知识服务平台和PubMed中1996—2015年间发表文献，分别得2 873、1 244和84篇文献，依据纳入排除标准共纳入30篇文献，对纳入文献的基本信息、研究对象、经济负担分析指标及主要费用结果等进行摘录和汇总分析，费用数据均贴现至2013年值。 结果： 30篇文献中，包括29项个体研究和1项人群研究，共覆盖14个省份，16篇发表于2011—2015年；29篇个体研究中报告直接医疗、直接非医疗和间接经济负担的文献分别有29、1和2篇；主要费用指标为例均（22篇）、次均（9篇）及日均（11篇）。直接医疗费用结果提示，中国胃癌1996—2013年中位例均费用为7 387~28 743元人民币，年均增长率为1.7%；2003—2013年中位次均费用为18 504~41 871元人民币，年均增长率为5.5%；1996—2012年中位日均费用为313~1 445元人民币，年均增长率为3.7%；且直接医疗费用存在地区差异。 结论： 我国既往20年的胃癌经济负担研究仍以个体和地区层面居多；直接医疗费用呈增长趋势，且存在地区差异；直接非医疗费用和间接经济负担数据匮乏。.
Keywords: Cost of illness; Economic burden; Expenditure; Stomach neoplasms.