Modulating conversion of isoflavone glycosides to aglycones using crude beta-glycosidase extracts from almonds and processed soy

Food Chem. 2017 Dec 15:237:685-692. doi: 10.1016/j.foodchem.2017.05.122. Epub 2017 May 24.

Abstract

Food processing alters the physicochemical state of soy which can enhance chemical and enzymatic conversion of isoflavones to their aglycone forms. This study investigated the role of β-glycosidase from processed soy-ingredient mixture (SIM) or almonds, and examined the impact of isoflavone composition in mediating conversion to aglycones. β-Glycosidase activity was quantified using p-nitrophenol-β-d-glucopyranoside and SIM isoflavone extracts. Almond β-glycosidase activity was significantly (p<0.001) reduced after roasting (99% reduction) or steaming (97% reduction) compared to raw almonds. SIM β-glycosidase activity, however, increased, with steaming by 66% (p<0.001) and with roasting by 52% (p=0.022), compared to raw SIM. After incubation with β-glycosidase, percentage of aglycone (total aglycone/total isoflavones) in SIM isoflavone extracts increased significantly in raw (35%), fermented (48%), roasted (88%) and steamed (91%) SIM, compared to their initial (∼5%) compositions. Manipulation of β-glycosidase activity and isoflavone composition can be used to modulate aglycone content in soy food products.

Keywords: Almonds; Isoflavones; Processing; Soy; β-Glycosidase.

MeSH terms

  • Glycoside Hydrolases / metabolism*
  • Glycosides / metabolism*
  • Isoflavones
  • Nitrophenols
  • Prunus dulcis*

Substances

  • Glycosides
  • Isoflavones
  • Nitrophenols
  • Glycoside Hydrolases
  • 4-nitrophenol