Background: Comorbid depression in Hepatitis B virus (HBV) is common. Developing accurate and time- efficient tools to measure depressive symptoms in HBV is important for research and clinical practice in China.
Aims: This study tested the psychometric properties of the Chinese version of the 16-item Quick Inventory of Depressive Symptomatology (QIDS-SR) in HBV patients.
Methods: The study recruited 245 depressed patients with HBV and related liver disease. The severity of depressive symptoms was assessed with the Montgomery-Asberg Depression Rating Scale (MADRS) and the QIDS-SR.
Results: Internal consistency (Cronbach's alpha) was 0.796 for QIDS-SR. The QIDS-SR total score was significantly correlated with the MADRS total score (r=0.698, p<0.001). The QIDS-SR showed unidimensional measurement properties in exploratory factor analysis.
Conclusions: The QIDS-SR (Chinese version) has good psychometric properties in HBV patients and appears to be useful in assessing depression in clinical settings.
背景: 乙型肝炎病毒（HBV）感染伴发抑郁症是一种 常见的现象。建立精确并且有时效的工具，用以评估 HBV 患者抑郁症状，对研究和临床实践是非常重要的。.
目的: 这项研究测试了抑郁症状快速评定量表自评版 （QIDS-SR）在乙型肝炎患者中使用的心理测量学特性.
方法: 这项研究招募了245 名患有乙型肝炎病毒和 相关肝病的抑郁症患者。采用蒙特玛莉抑郁评定量表 （MADRS）和QIDS-SR 评估抑郁症状的严重程度。 段钟平，项玉涛.
结果: QIDS-SR 的内部一致性（(Cronbach α）为0.796. 其总分与MADRS 总分显著相关r=0.698, p<0.001）。 探索性因素分析的QIDS-SR 显示一维测量性能.
结论: QIDS-SR（中文版）在乙型肝炎患者中有良好 的心理测量学特性，并且在评估临床抑郁症方面是有 用的。.
Keywords: Depressive symptoms; Hepatitis B Virus; QIDS-SR; psychometric properties.