Kyoto Congestive Heart Failure (KCHF) study: rationale and design

Erika Yamamoto; Takao Kato; Neiko Ozasa; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Takeshi Kitai; Takeshi Morimoto; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Tsuneaki Kawashima; Yasuyo Motohashi; Mitsunori Kawato; Mamoru Toyofuku; Yukihito Sato; Koichiro Kuwahara; Tetsuo Shioi; Takeshi Kimura; KCHF study investigators

doi:10.1002/ehf2.12138

Kyoto Congestive Heart Failure (KCHF) study: rationale and design

ESC Heart Fail. 2017 Aug;4(3):216-223. doi: 10.1002/ehf2.12138. Epub 2017 Feb 17.

Authors

Erika Yamamoto¹, Takao Kato¹, Neiko Ozasa¹, Hidenori Yaku¹, Yasutaka Inuzuka², Yodo Tamaki³, Takeshi Kitai⁴, Takeshi Morimoto⁵, Ryoji Taniguchi⁶, Moritake Iguchi⁷, Masashi Kato⁸, Mamoru Takahashi⁹, Toshikazu Jinnai¹⁰, Tomoyuki Ikeda¹¹, Kazuya Nagao¹², Takafumi Kawai¹³, Akihiro Komasa¹⁴, Ryusuke Nishikawa¹⁵, Yuichi Kawase¹⁶, Takashi Morinaga¹⁷, Tsuneaki Kawashima¹⁸, Yasuyo Motohashi¹⁹, Mitsunori Kawato²⁰, Mamoru Toyofuku¹⁹, Yukihito Sato⁶, Koichiro Kuwahara¹, Tetsuo Shioi¹, Takeshi Kimura¹; KCHF study investigators

Affiliations

¹ Department of Cardiovascular Medicine, Graduate School of Medicine Kyoto University, Kyoto, Japan.
² Department of Cardiovascular Medicine, Shiga Medical Center for Adult, Moriyama, Shiga, Japan.
³ Division of Cardiology, Tenri Hospital, Nara, Japan.
⁴ Department of Cardiology, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan.
⁵ Department of Clinical Epidemiology, Hyogo College of Medicine, Kobe, Hyogo, Japan.
⁶ Department of Cardiology, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Hyogo, Japan.
⁷ National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
⁸ Mitsubishi Kyoto Hospital, Kyoto, Japan.
⁹ Shimabara Hospital, Kyoto, Japan.
¹⁰ Japanese Red Cross Otsu Hospital, Otsu, Shiga, Japan.
¹¹ Hikone Municipal Hospital, Hikone, Shiga, Japan.
¹² Osaka Red Cross Hospital, Osaka, Japan.
¹³ Kishiwada City Hospital, Osaka, Japan.
¹⁴ Kansai Electric Power Hospital, Osaka, Japan.
¹⁵ Shizuoka General Hospital, Shizuoka, Japan.
¹⁶ Kurashiki Central Hospital, Okayama, Japan.
¹⁷ Kokura Memorial Hospital, Fukuoka, Japan.
¹⁸ Second Okamoto General Hospital, Kyoto, Japan.
¹⁹ Japanese Res Cross Wakayama Medical Center, Wakayama, Japan.
²⁰ Nishi-Kobe Medical Center, Kobe, Hyogo, Japan.

Abstract

Aims: Over the last decade, major developments in medicine have led to significant changes in the clinical management of heart failure patients. This study was designed to evaluate the recent trends in clinical characteristics, management, and short-term and long-term prognosis of patients with acute decompensated heart failure (ADHF) in Japan.

Methods and results: The Kyoto Congestive Heart Failure study is a prospective, observational, multicentre cohort study, enrolling consecutive ADHF patients from 19 participating hospitals in Japan from November 2014 to March 2016. A total of 4000 patients will be enrolled into the study and patients' anthropometric, socio-economic, and clinical data from hospital admission to discharge will be collected. In addition, in a pre-determined subgroup of patients (n=1500), a longitudinal follow-up for 2 years is scheduled.

Conclusions: The Kyoto Congestive Heart Failure study will provide valuable information regarding patients with ADHF in the real-world clinical practice of Japan and will be indispensable for future clinical and policy decision-making with respect to heart failure.

Keywords: Cohort study; Decompensation; Heart failure; Prognosis.