Pericardiectomy for Constrictive Pericarditis: An Institution's 21 Years Experience

Thorac Cardiovasc Surg. 2018 Nov;66(8):645-650. doi: 10.1055/s-0037-1604303. Epub 2017 Aug 6.

Abstract

Background: The aim of this retrospective study was to evaluate our experience with the surgical pericardiectomy procedure for patients suffering from isolated severe constrictive pericarditis.

Methods: From 1995 to 2016, 39 patients underwent isolated pericardiectomy for constrictive pericarditis. Fifteen patients were excluded because of concomitant surgery. There were 31 male (79.5%) patients and 8 female (20.5%) patients, 28 to 76 years old (mean, 56.6 ± 13.6 years). The underlying etiologies were idiopathic pericarditis (74.5%), infection (10%), rheumatic disorders (8%), status post cardiac surgery (2.5%), tuberculosis (2.5%), and status post mediastinal irradiation (2.5%).

Results: Pericardiectomy was performed through midline sternotomy in all cases. Sixteen patients (41%) underwent pericardiectomy electively employing cardiopulmonary bypass with the heart beating, and 23 patients (59%) had surgery without extracorporeal circulation (ECC). The overall 30-day mortality rate was 50% if cardiopulmonary bypass was used (13.8% since 2007). If surgery was performed without a heart-lung machine, mortality was 0%. On-pump patients had a significantly longer intensive care unit (ICU) stay (12 ± 9 vs. 4 ± 4 days, p = 0.013). Likewise, the duration of mechanical ventilation was much longer (171 ± 246 vs. 21 ± 40 hours, p = 0.04). The hospital stay was comparable with 28 ± 10 and 24 ± 18 days (p = 0.21).

Conclusion: The present study demonstrates that pericardiectomy, without the use of cardiopulmonary bypass as treatment for constrictive pericarditis, is a safe procedure with an excellent outcome in critically ill patients.

MeSH terms

  • Adult
  • Aged
  • Cardiopulmonary Bypass
  • Extracorporeal Membrane Oxygenation
  • Female
  • Germany
  • Humans
  • Length of Stay
  • Male
  • Middle Aged
  • Pericardiectomy* / adverse effects
  • Pericardiectomy* / mortality
  • Pericarditis, Constrictive / diagnosis
  • Pericarditis, Constrictive / mortality
  • Pericarditis, Constrictive / surgery*
  • Postoperative Complications / etiology
  • Postoperative Complications / therapy
  • Retrospective Studies
  • Risk Factors
  • Severity of Illness Index
  • Sternotomy
  • Time Factors
  • Treatment Outcome