An Unusual Case of Penile Prostate Cancer Uncovered by Multiparametric MRI and PSMA-Targeted 18F-DCFPyL PET/CT

Clin Nucl Med. 2017 Oct;42(10):e441-e443. doi: 10.1097/RLU.0000000000001785.

Abstract

Multiparametric MRI (mpMRI) is currently the test of choice for imaging sites of prostate cancer located within the pelvis. However, molecular imaging with PET radiotracers that bind to prostate-specific membrane antigen is increasingly being used for this purpose and may compliment mpMRI findings. We present a case of a 59-year-old man with elevated postprostatectomy serum prostate-specific antigen level who was found on both mpMRI and prostate-specific membrane antigen-targeted PET to harbor residual prostate cancer in the corpus spongiosum along the proximal urethra.

Publication types

  • Case Reports

MeSH terms

  • Antigens, Surface / metabolism*
  • Glutamate Carboxypeptidase II / metabolism*
  • Humans
  • Lysine / analogs & derivatives*
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Penile Neoplasms / complications*
  • Penile Neoplasms / diagnostic imaging*
  • Penile Neoplasms / metabolism
  • Positron Emission Tomography Computed Tomography*
  • Prostatic Neoplasms / complications*
  • Urea / analogs & derivatives*

Substances

  • 2-(3-(1-carboxy-5-((6-fluoropyridine-3-carbonyl)amino)pentyl)ureido)pentanedioic acid
  • Antigens, Surface
  • Urea
  • FOLH1 protein, human
  • Glutamate Carboxypeptidase II
  • Lysine