Absent cardiac and muscle sympathetic nerve activities involvement in Ross syndrome: A follow-up study

Auton Neurosci. 2017 Dec:208:161-164. doi: 10.1016/j.autneu.2017.08.003. Epub 2017 Aug 9.

Abstract

Purpose: Ross syndrome (RS) is characterized by selective involvement of post-ganglionic skin sympathetic nerve fibres. We report a follow-up study in 4 patients to clarify whether in RS autonomic dysfunction spreads affecting also cardiovascular system.

Methods: The patients underwent cardiovascular reflexes (CVR) and microneurography recording of muscle sympathetic nerve activity (MSNA) for a follow-up mean period of 5years.

Results: CVR and MSNA were normal at baseline and unchanged over the follow-up.

Conclusions: Cardiovascular autonomic system is spared in RS differently from skin autonomic activity dysfunction which progress over time. However, before drawing any definite conclusion, a large cohort of patients needs to be studied.

Keywords: Autonomic; Cardiovascular reflexes; Microneurography; Ross syndrome.

MeSH terms

  • Adult
  • Aged
  • Autonomic Nervous System Diseases / physiopathology*
  • Autonomic Nervous System Diseases / therapy
  • Cardiovascular System / physiopathology*
  • Female
  • Follow-Up Studies
  • Humans
  • Hypohidrosis / physiopathology*
  • Hypohidrosis / therapy
  • Male
  • Middle Aged
  • Reflex / physiology
  • Sympathetic Nervous System / physiopathology*
  • Syndrome
  • Tonic Pupil / physiopathology*
  • Tonic Pupil / therapy