Right Ventricular-Pulmonary Vascular Interactions

Diana M Tabima; Jennifer L Philip; Naomi C Chesler

doi:10.1152/physiol.00040.2016

Right Ventricular-Pulmonary Vascular Interactions

Physiology (Bethesda). 2017 Sep;32(5):346-356. doi: 10.1152/physiol.00040.2016.

Authors

Diana M Tabima¹, Jennifer L Philip^{1

2}, Naomi C Chesler³

Affiliations

¹ Department of Biomedical Engineering, University of Wisconsin-Madison College of Engineering, Madison, Wisconsin; and.
² Department of Surgery, University of Wisconsin-Madison, Madison, Wisconsin.
³ Department of Biomedical Engineering, University of Wisconsin-Madison College of Engineering, Madison, Wisconsin; and [email protected].

Abstract

Accurate and comprehensive evaluation of right ventricular (RV)-pulmonary vascular (PV) interactions is critical to the assessment of cardiopulmonary function, dysfunction, and failure. Here, we review methods of quantifying RV-PV interactions and experimental results from clinical trials as well as large- and small-animal models based on pressure-volume analysis. We conclude by outlining critical gaps in knowledge that should drive future studies.

Publication types

Review
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Heart Ventricles / physiopathology*
Humans
Lung / blood supply*
Pulmonary Veins / physiology*

Abstract

Publication types

MeSH terms

Grants and funding