Extracorporeal membrane oxygenation (ECMO) was first introduced for patients with acute respiratory distress syndrome (ARDS) in the 1970s. However, enthusiasm was tempered due to the high mortality seen at that time. The use of ECMO has grown considerably in recent years due to technological advances and the evidence suggesting potential benefit. While the efficacy of ECMO has yet to be rigorously demonstrated with high-quality evidence, it has the potential not only to have a substantial impact on outcomes, including mortality, but also to change the paradigm of ARDS management.
Keywords: Acute respiratory distress syndrome (ARDS); extracorporeal carbon dioxide removal (ECCO2R); extracorporeal life support; extracorporeal membrane oxygenation (ECMO); respiratory failure.