Endobronchial melanoma metastasis 40 years after the excision of the primary cutaneous tumor: A case report

Medicine (Baltimore). 2017 Aug;96(34):e7931. doi: 10.1097/MD.0000000000007931.

Abstract

Rationale: Endobronchial melanoma metastases are rare, comprising 4.5% of all endobronchial metastases. They are diagnosed at a median time of 48 months from primary tumor presentation, and survival of these patients is poorer when accompanied by other metastatic sites or malignant pleural effusion. We present a case of endobronchial melanoma metastasis happening 40 years after the initial diagnosis. The need of adjuvant techniques in the diagnosis of this tumor is highlighted and a short review on this rare phenomenon is provided.

Patients concerns: An 83-year old nonsmoking woman, presented with dyspnea.

Diagnoses: Left lung atelectasis was found.

Interventions: Endobronchial resection of a tumor of the left main stem bronchus was achieved by rigid bronchoscopy under general anesthesia with complete reventilation of the left lung.

Outcomes: Histopathological, immunohistochemical and molecular diagnostics of the resected tumor led to a diagnosis of an endobronchial melanoma metastasis.

Lessons: Melanoma is a type of tumor that cannot be regarded as cured even after long disease-free periods, and thus, any new symptomatology in these patients warrants stringent work up.

Publication types

  • Case Reports

MeSH terms

  • Age of Onset
  • Aged, 80 and over
  • Bronchial Neoplasms / secondary*
  • Female
  • Humans
  • Melanoma / pathology*
  • Skin Neoplasms / pathology*