Cardioscopically Guided Beating Heart Surgery: Paravalvular Leak Repair

Ann Thorac Surg. 2017 Sep;104(3):1074-1079. doi: 10.1016/j.athoracsur.2017.03.028.

Abstract

Purpose: There remains a paucity of direct visualization techniques for beating-heart intracardiac procedures. To address this need, we evaluated a novel cardioscope in the context of aortic paravalvular leaks (PVLs) localization and closure.

Description: A porcine aortic PVL model was created using a custom-made bioprosthetic valve, and PVL presence was verified by epicardial echocardiography. Transapical delivery of occlusion devices guided solely by cardioscopy was attempted 13 times in a total of three pigs. Device retrieval after release was attempted six times. Echocardiography, morphologic evaluation, and delivery time were used to assess results.

Evaluation: Cardioscopic imaging enabled localization of PVLs via visualization of regurgitant jet flow in a paravalvular channel at the base of the prosthetic aortic valve. Occluders were successfully placed in 11 of 13 attempts (84.6%), taking on average 3:03 ± 1:34 min. Devices were cardioscopically removed successfully in three of six attempts (50%), taking 3:41 ± 1:46 min. No damage to the ventricle or annulus was observed at necropsy.

Conclusions: Cardioscopy can facilitate intracardiac interventions by providing direct visualization of anatomic structures inside the blood-filled, beating-heart model.

MeSH terms

  • Animals
  • Aortic Valve Insufficiency / diagnosis
  • Aortic Valve Insufficiency / surgery*
  • Cardiac Catheterization / methods*
  • Cardiac Surgical Procedures / methods*
  • Disease Models, Animal
  • Echocardiography, Three-Dimensional
  • Echocardiography, Transesophageal
  • Endoscopy / methods*
  • Heart Valve Prosthesis / adverse effects*
  • Mitral Valve Insufficiency / diagnosis
  • Mitral Valve Insufficiency / surgery*
  • Prosthesis Failure
  • Reoperation / methods
  • Swine