Predicting Postpartum Hemorrhage (PPH) during Cesarean Delivery Using the Leicester PPH Predict Tool: A Retrospective Cohort Study

Am J Perinatol. 2018 Jan;35(2):163-169. doi: 10.1055/s-0037-1606332. Epub 2017 Aug 28.

Abstract

Objective: The aim of the present study was to develop a toolkit combining various risk factors to predict the risk of developing a postpartum hemorrhage (PPH) during a cesarean delivery.

Study design: A retrospective cohort study of 24,230 women who had cesarean delivery between January 2003 and December 2013 at a tertiary care teaching hospital within the United Kingdom serving a multiethnic population. Data were extracted from hospital databases, and risk factors for PPH were identified. Hothorn et al recursive partitioning algorithm was used to infer a conditional decision tree. For each of the identified combinations of risk factors, two probabilities were calculated: the probability of a patient producing ≥1,000 and ≥ 2,000 mL blood loss.

Results: The Leicester PPH predict score was then tested on the randomly selected remaining 25% (n = 6,095) of the data for internal validity. Reliability testing showed an intraclass correlation of 0.98 and mean absolute error of 239.8 mL with the actual outcome.

Conclusion: The proposed toolkit enables clinicians to predict the risk of postpartum hemorrhage. As a result, preventative measures for postpartum hemorrhage could be undertaken. Further external validation of the current toolkit is required.

Publication types

  • Validation Study

MeSH terms

  • Adult
  • Cesarean Section / adverse effects*
  • Female
  • Humans
  • Postoperative Complications / diagnosis*
  • Postoperative Complications / epidemiology*
  • Postpartum Hemorrhage / diagnosis*
  • Postpartum Hemorrhage / epidemiology*
  • Pregnancy
  • Reproducibility of Results
  • Retrospective Studies
  • Risk Assessment / methods
  • Risk Factors
  • Tertiary Care Centers
  • United Kingdom / epidemiology