Disseminated Pseudomonas aeruginosa sepsis as presenting diagnosis of X-linked agammaglobulinaemia in a previously well 16-month-old child

BMJ Case Rep. 2017 Aug 29:2017:bcr2017221006. doi: 10.1136/bcr-2017-221006.

Abstract

We report a previously healthy 16-month-old child who presented to us with membranous pharyngitis and ecthyma gangrenosum. In this patient, Pseudomonas aeruginosa was isolated from throat swab, cerebrospinal fluid, skin swab, urine, blood and synovial fluid in a single admission. In further workup, this child was diagnosed as a case of X-linked agammaglobulinaemia. The child was treated successfully with antipseudomonal antibiotics for 6 weeks and intravenous immunoglobulin.

Keywords: immunology; infectious diseases; paediatrics.

Publication types

  • Case Reports

MeSH terms

  • Agammaglobulinemia / microbiology*
  • Anti-Bacterial Agents / therapeutic use
  • Genetic Diseases, X-Linked / microbiology*
  • Humans
  • Infant
  • Male
  • Pseudomonas Infections / microbiology*
  • Pseudomonas aeruginosa*
  • Sepsis / microbiology*

Substances

  • Anti-Bacterial Agents

Supplementary concepts

  • Bruton type agammaglobulinemia