[Correspondence analysis between traditional commercial specifications and quantitative quality indices of Notopterygii Rhizoma et Radix]

Zhongguo Zhong Yao Za Zhi. 2016 Mar;41(5):793-801. doi: 10.4268/cjcmm20160506.
[Article in Chinese]

Abstract

This paper aims to explore a comprehensive assessment method combined traditional Chinese medicinal material specifications with quantitative quality indicators. Seventy-six samples of Notopterygii Rhizoma et Radix were collected on market and at producing areas. Traditional commercial specifications were described and assigned, and 10 chemical components and volatile oils were determined for each sample. Cluster analysis, Fisher discriminant analysis and correspondence analysis were used to establish the relationship between the traditional qualitative commercial specifications and quantitative chemical indices for comprehensive evaluating quality of medicinal materials, and quantitative classification of commercial grade and quality grade. A herb quality index (HQI) including traditional commercial specifications and chemical components for quantitative grade classification were established, and corresponding discriminant function were figured out for precise determination of quality grade and sub-grade of Notopterygii Rhizoma et Radix. The result showed that notopterol, isoimperatorin and volatile oil were the major components for determination of chemical quality, and their dividing values were specified for every grade and sub-grade of the commercial materials of Notopterygii Rhizoma et Radix. According to the result, essential relationship between traditional medicinal indicators, qualitative commercial specifications, and quantitative chemical composition indicators can be examined by K-mean cluster, Fisher discriminant analysis and correspondence analysis, which provide a new method for comprehensive quantitative evaluation of traditional Chinese medicine quality integrated traditional commodity specifications and quantitative modern chemical index.

Keywords: Notopterygii Rhizoma et Radix; herb quality index(HQI); quality index; quality standard; traditional commercial specifications.

MeSH terms

  • Apiaceae / chemistry*
  • Apiaceae / classification
  • China
  • Chromatography, High Pressure Liquid
  • Drugs, Chinese Herbal / analysis*
  • Drugs, Chinese Herbal / economics
  • Furocoumarins / analysis
  • Furocoumarins / economics
  • Medicine, Chinese Traditional / economics
  • Rhizome / chemistry
  • Rhizome / classification

Substances

  • Drugs, Chinese Herbal
  • Furocoumarins
  • isoimperatorin