Hepatic transplantation in Europe. First Report of the European Liver Transplant Registry

Lancet. 1987 Sep 19;2(8560):674-6. doi: 10.1016/s0140-6736(87)92453-6.

Abstract

At the 32 European centres where livers are transplanted the actuarial survival rate for 1218 patients was 44% at 1 year and 41% at 2 years. Perioperative mortality (30 days) was 30%. Recipients aged under 15 years had a higher survival rate than those aged over 15; the differences were 22% at 1 year and 32% at 2 years. For the 97 patients who received two or more liver grafts, actuarial survival was 27.7% at 1 and 2 years. Two-thirds of the transplantations were done since 1984. Since then the best results have been obtained for biliary atresia (88 cases; survival rates at 30 days, 1 year, and 2 years were 87%, 74%, and 68%). Primary biliary cirrhosis was the commonest benign indication for transplantation, with survival of 64% at 1 and 2 years. The proportion of transplantations that were done for patients with hepatocellular carcinoma was smaller after than before 1984; among transplantations done in adults after 1984, those done because of hepatocellular carcinoma gave the best perioperative survival rate (76%) but the worst 2 year survival (30.8%).

MeSH terms

  • Actuarial Analysis
  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Biliary Atresia / surgery
  • Carcinoma, Hepatocellular / surgery
  • Europe
  • Evaluation Studies as Topic
  • Humans
  • Infant
  • Liver Cirrhosis, Biliary / surgery
  • Liver Neoplasms / surgery
  • Liver Transplantation*
  • Middle Aged
  • Registries
  • Surveys and Questionnaires
  • Transplantation, Homologous / mortality