Association between mode of delivery and astigmatism in preschool children

Acta Ophthalmol. 2018 Mar;96(2):e218-e221. doi: 10.1111/aos.13552. Epub 2017 Sep 9.

Abstract

Purpose: To determine whether mode of delivery has any impact on astigmatism.

Methods: This case-control study was performed in the Department of Ophthalmology in 2015. Exposure was mode of delivery [vaginal delivery (VD) or caesarean section (CS), which here included both elective and emergency CS]. Outcome was astigmatism (≥2.5 D), which was determined by cycloplegic refraction. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were computed to assess the associations between mode of delivery and astigmatism from logistic regression models.

Results: Of the 659 children studied here (341 boys; mean age, 4.37 years), 440 were born by CS and 219 by VD. The incidence of severe astigmatism (≥2.5 D) in the CS and VD groups was 22.06% and 13.24%, respectively. Children delivered by CS had a 77.9% higher risk of severe astigmatism compared with vaginally delivered children (OR = 1.779; 95% CI, 1.121 to 2.824). After dividing CS into elective CS and emergency CS, children delivered by elective CS had an 87.3% increased risk of severe astigmatism (OR = 1.873; 95% CI, 1.157 to 3.032), but children delivered by emergency CS did not differ from vaginally delivered children. In addition, the children whose mothers had histories of breastfeeding had a 44.6% lower risk of severe astigmatism than children whose mother did not breastfeed them (OR = 0.554, 95% CI, 0.335-0.914).

Conclusion: Birth by CS, especially elective CS, increases the risk of severe astigmatism (≥2.50 D) in childhood.

Keywords: astigmatism; breastfeeding; caesarean section; vaginal delivery.

MeSH terms

  • Astigmatism / epidemiology*
  • Case-Control Studies
  • Cesarean Section / statistics & numerical data
  • Child
  • Child, Preschool
  • China / epidemiology
  • Delivery, Obstetric / statistics & numerical data*
  • Extraction, Obstetrical / statistics & numerical data
  • Female
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Male
  • Odds Ratio
  • Risk Assessment
  • Surveys and Questionnaires