A frameshift mutation in BRCA1 leads to hereditary breast and ovarian cancer in one part of a family and to familial pancreatic cancer in another

Breast Cancer Res Treat. 2018 Jan;167(1):305-307. doi: 10.1007/s10549-017-4500-5. Epub 2017 Sep 12.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • BRCA1 Protein / genetics*
  • Breast Neoplasms / epidemiology
  • Breast Neoplasms / genetics*
  • Breast Neoplasms / pathology
  • Female
  • Frameshift Mutation / genetics
  • Genetic Predisposition to Disease
  • Humans
  • Loss of Heterozygosity / genetics
  • Middle Aged
  • Ovarian Neoplasms / epidemiology
  • Ovarian Neoplasms / genetics*
  • Ovarian Neoplasms / pathology
  • Pancreatic Neoplasms / epidemiology
  • Pancreatic Neoplasms / genetics*
  • Pancreatic Neoplasms / pathology
  • Pedigree

Substances

  • BRCA1 Protein
  • BRCA1 protein, human