Abstract
Fever of unknown origin in a multiple sclerosis patient on immunomodulatory therapy was due to neoehrlichiosis The emerging tick-borne bacterium Candidatus Neoehrlichia mikurensis is the etiologic agent of neoehrlichiosis, a febrile illness that may be accompanied by vascular complications. Severe cases of neoehrlichiosis have been described in patients with hematologic malignancies and systemic rheumatic diseases. We present the first case of neoehrlichiosis in a patient with multiple sclerosis undergoing rituximab therapy.
MeSH terms
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Anaplasmataceae
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Anaplasmataceae Infections / complications
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Anaplasmataceae Infections / diagnosis*
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Anaplasmataceae Infections / drug therapy
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Anti-Bacterial Agents / therapeutic use
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Female
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Fever / microbiology
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Humans
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Immunologic Factors / therapeutic use
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Middle Aged
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Multiple Sclerosis / complications
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Multiple Sclerosis / drug therapy
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Polymerase Chain Reaction
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Rituximab / therapeutic use
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Tick-Borne Diseases / complications
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Tick-Borne Diseases / diagnosis*
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Tick-Borne Diseases / drug therapy
Substances
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Anti-Bacterial Agents
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Immunologic Factors
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Rituximab