Single-cell analyses to tailor treatments

Alex K Shalek; Mikael Benson

doi:10.1126/scitranslmed.aan4730

Single-cell analyses to tailor treatments

Sci Transl Med. 2017 Sep 20;9(408):eaan4730. doi: 10.1126/scitranslmed.aan4730.

Authors

Alex K Shalek^{1

2

3}, Mikael Benson⁴

Affiliations

¹ Institute for Medical Engineering & Science (IMES) and Department of Chemistry, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA. [email protected] [email protected].
² Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
³ Ragon Institute of Massachusetts General Hospital, MIT, and Harvard, Cambridge, MA 02139, USA.
⁴ The Centre for Personalised Medicine and Division of Pediatrics, Department of Clinical and Experimental Medicine, Linköping University, 58183 Linköping, Sweden. [email protected] [email protected].

Abstract

Single-cell RNA-seq could play a key role in personalized medicine by facilitating characterization of cells, pathways, and genes associated with human diseases such as cancer.

Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).

Publication types

Review

MeSH terms

Disease
Humans
Precision Medicine*
Sequence Analysis, RNA
Single-Cell Analysis / methods*
Translational Research, Biomedical

Abstract

Publication types

MeSH terms

Grants and funding