Neisseria meningitidis Serogroup X ST-5799 (ST-22 complex) in Turkey: A unique pediatric case

Hum Vaccin Immunother. 2018 Jan 2;14(1):209-212. doi: 10.1080/21645515.2017.1377380. Epub 2017 Dec 11.

Abstract

Although outbreaks of Neisseria meningitidis serogroup X occured in a couple of African countries, a limited number of serogroup X meningococcal cases were reported in America and Europe as well as Turkey. Additionally, serogroup X is still not represented in current conjugated meningococcal vaccines. Here, we describe the first pediatric case with meningitis caused by Neisseria meningitidis serogroup X ST-5799 (ST-22 complex) that formed a distinct lineage.

Keywords: Turkey; menengitis; pediatrics; phylogenetic network; sequence analyses.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • DNA, Bacterial / cerebrospinal fluid
  • DNA, Bacterial / isolation & purification
  • Drug Therapy, Combination / methods
  • Humans
  • Infant
  • Male
  • Meningitis, Meningococcal / diagnosis
  • Meningitis, Meningococcal / drug therapy
  • Meningitis, Meningococcal / immunology
  • Meningitis, Meningococcal / microbiology*
  • Neisseria meningitidis / genetics
  • Neisseria meningitidis / immunology*
  • Neisseria meningitidis / isolation & purification
  • Phylogeny
  • Serogroup*
  • Treatment Outcome
  • Turkey

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial