Small Circular Rep-Encoding Single-Stranded DNA Genomes in Peruvian Diarrhea Virome

Eda Altan; Juana Del Valle Mendoza; Xutao Deng; Tung G Phan; Mohammadreza Sadeghi; Eric L Delwart

doi:10.1128/genomeA.00822-17

Small Circular Rep-Encoding Single-Stranded DNA Genomes in Peruvian Diarrhea Virome

Genome Announc. 2017 Sep 21;5(38):e00822-17. doi: 10.1128/genomeA.00822-17.

Authors

Eda Altan^{1

2}, Juana Del Valle Mendoza^{3

4}, Xutao Deng^{1

2}, Tung G Phan^{1

2}, Mohammadreza Sadeghi^{1

2

5}, Eric L Delwart^{6

2}

Affiliations

¹ Blood Systems Research Institute, San Francisco, California, USA.
² Department of Laboratory Medicine, University of California at San Francisco, San Francisco, California, USA.
³ School of Medicine, Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
⁴ Instituto de Investigación Nutricional, Lima, Peru.
⁵ Department of Virology, University of Helsinki, Helsinki, Finland.
⁶ Blood Systems Research Institute, San Francisco, California, USA [email protected].

Abstract

Metagenomic analysis of diarrhea samples revealed the presence of numerous human enteric viruses and small circular Rep-encoding single-stranded DNA (CRESS-DNA) genomes. One such genome was related to smacoviruses, while eight others were related to genomes reported in the feces of different mammals. The tropism of these CRESS-DNA viruses remains unknown.