Practical considerations in enhancing LC-MS sensitivity for therapeutic protein bioanalysis

Bioanalysis. 2017 Sep;9(18):1353-1356. doi: 10.4155/bio-2017-4982.

Shaolian Zhou¹, Faye Vazvaei², Luca Ferrari¹, Jun Qu^{3

4}

¹ Roche Pharmaceutical Research & Early Development, Roche Innovation Center Basel, Basel, Switzerland.
² Roche Pharmaceutical Research & Early Development, Roche Innovation Center New York, New York, NY 10016, USA.
³ The Department of Pharmaceutical Sciences, School of Pharmacy & Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, NY 14214, USA.
⁴ New York State Center of Excellence in Bioinformatics & Life Sciences, Buffalo, NY 14203, USA.

No abstract available

Keywords: LC–MS; protein bioanalysis; sensitivity; signature peptide.

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