Aqueous Extracts of Wild Mushrooms Show Antimicrobial and Antiadhesion Activities against Bacteria and Fungi

Phytother Res. 2017 Dec;31(12):1971-1976. doi: 10.1002/ptr.5934. Epub 2017 Sep 28.

Abstract

Mushrooms represent promising sources of novel bioactive compounds and can be applied as innovative strategies to control microbial contamination and infection via the food chain. We characterized aqueous extracts from 21 wild basidiomycete mushrooms and the cultivated oyster mushroom, Pleurotus ostreatus, as putative sources of antimicrobial and antiadhesive compounds. Broth microdilutions and adhesion to a polystyrene surface were evaluated on Gram-positive and Gram-negative bacteria and on fungi. The aqueous extracts tested showed antimicrobial and antiadhesive activities against these microorganisms. Biochemical analyses of the P. ostreatus extract indicated the involvement of several compounds with different molecular masses. Copyright © 2017 John Wiley & Sons, Ltd.

Keywords: adhesion; antiadhesion activity; antimicrobial activity; basidiomycete.

MeSH terms

  • Agaricales / chemistry*
  • Anti-Bacterial Agents / therapeutic use*
  • Anti-Infective Agents / therapeutic use*

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents