Objective: To review the cognitive and behavioral features of the different atypical parkinsonian syndromes in which motor symptoms dominate early clinical symptomology: multiple systems atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD). The impact of cognitive and behavioral deficits on quality of life, associations between neuropsychological and neuropsychiatric findings and brain imaging, and cognitive and behavioral symptom management are also discussed.
Method: A review of the available MSA, PSP, and CBD literature was conducted, with emphasis given to studies investigating the cognitive and behavioral features of the syndromes.
Results: Although the three reviewed atypical parkinsonian syndromes share many similarities to each other and PD from a neuropsychological perspective, differences in prevalence and severity of cognitive impairment and patterns of performance on neuropsychological and neuropsychiatric measures exist in the research literature.
Conclusions: Cognitive and behavioral features are early and pervasive aspects of MSA, PSP, and CBD.
Keywords: Executive function; Fluency (verbal/nonverbal); Movement disorders; Parkinson's disease.
© The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: [email protected].