Functional decline in the elderly with MCI: Cultural adaptation of the ADCS-ADL scale

Rev Assoc Med Bras (1992). 2017 Jul;63(7):590-599. doi: 10.1590/1806-9282.63.07.590.

Abstract

Objective: Translate, transcultural adaptation and application to Brazilian Portuguese of the Alzheimer's Disease Cooperative Study - Activities of Daily Living (ADCS-ADL) scale as a cognitive screening instrument.

Method: We applied the back translation added with pretest and bilingual methods. The sample was composed by 95 elderly individuals and their caregivers. Thirty-two (32) participants were diagnosed as mild cognitive impairment (MCI) patients, 33 as Alzheimer's disease (AD) patients and 30 were considered as cognitively normal individuals.

Results: There were only little changes on the scale. The Cronbach alpha coefficient was 0.89. The scores were 72.9 for control group, followed by MCI (65.1) and by AD (55.9), with a p-value < 0.001. The ROC curve value was 0.89. We considered a cut point of 72 and we observed a sensibility of 86.2%, specificity of 70%, positive predictive value of 86.2%, negative predictive value of 70%, positive likelihood ratio of 2.9 and negative likelihood ratio of 0.2.

Conclusion: ADCS-ADL scale presents satisfactory psychometric properties to discriminate between MCI, AD and normal cognition.

MeSH terms

  • Activities of Daily Living
  • Aged
  • Alzheimer Disease / diagnosis
  • Alzheimer Disease / physiopathology
  • Brazil
  • Case-Control Studies
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / physiopathology
  • Cross-Cultural Comparison
  • Female
  • Geriatric Assessment / methods
  • Humans
  • Male
  • ROC Curve
  • Sensitivity and Specificity
  • Severity of Illness Index
  • Surveys and Questionnaires*
  • Translations