Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses among haemodialysis patients in two newly opened centres in Cameroon

Pan Afr Med J. 2017 Jul 31:27:235. doi: 10.11604/pamj.2017.27.235.13121. eCollection 2017.

Abstract

Introduction: Haemodialysis (HD) patients are potentially susceptible to infection with blood borne viral agents especially; Human Immunodeficiency Virus (HIV), hepatitis B (HBV) and hepatitis C Viruses (HCV), compared to the general population. We described their epidemiology in two newly created haemodialysis units in Cameroon: the Buea and Bamenda haemodialysis centres.

Methods: A cross sectional study: included were patients who had spent at least three months in haemodialysis. HBV, HCV and HIV serologies were determined and patients' characteristics extracted from patient's records.

Results: We included 104 participants (44 in Buea and 60 in Bamenda). Mean age was 48 years and 65.4% were men. Median duration in dialysis was 14 months. One of the three viral markers was present in 40.1% of patients. The hepatitis B surface antigen, anti-HCV and anti-HIV antibody prevalence were respectively 10.6%, 19.2%, 13.5%. A history of sexually transmitted infection was the only variable associated with anti-HIV antibody positivity.

Conclusion: The sero-prevalence of HBsAg, HCV and HIV are high in the two centres. HIV prevalence may have reflected its etiology as a cause of ESKD. HCV remains a cause for concern and needs further evaluation. There is urgent need for the implementation of preventive and control measures.

Keywords: HIV; Haemodialysis; Prevalence; hepatitis B; hepatitis C.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Cameroon / epidemiology
  • Cross-Sectional Studies
  • Female
  • HIV Antibodies / blood
  • HIV Infections / epidemiology*
  • Hepatitis B / epidemiology*
  • Hepatitis B Surface Antigens / blood
  • Hepatitis C / epidemiology*
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Renal Dialysis*
  • Seroepidemiologic Studies

Substances

  • HIV Antibodies
  • Hepatitis B Surface Antigens