Factors Associated With All-Cause Mortality Among Patients With Multidrug-Resistant Tuberculosis-United States, 1993-2013

Clin Infect Dis. 2017 Nov 13;65(11):1924-1926. doi: 10.1093/cid/cix667.

Abstract

We assessed characteristics associated with all-cause mortality among US patients with multidrug-resistant tuberculosis. Mortality decreased from 31% during 1993-2002 to 11% during 2003-2013. Directly observed therapy coverage increased from 74% to 95% and was protective against all-cause mortality after accounting for demographics, clinical characteristics, human immunodeficiency virus status, and period of treatment.

Keywords: United States; mortality; multidrug-resistant; tuberculosis.

MeSH terms

  • Adult
  • Antitubercular Agents / therapeutic use
  • Demography
  • Directly Observed Therapy
  • Female
  • Humans
  • Male
  • Tuberculosis, Multidrug-Resistant / epidemiology*
  • Tuberculosis, Multidrug-Resistant / etiology
  • Tuberculosis, Multidrug-Resistant / microbiology
  • Tuberculosis, Multidrug-Resistant / mortality*
  • United States / epidemiology

Substances

  • Antitubercular Agents