BRAF and NRAS mutations in circulating Langerhans-like CD1a⁺ cells in a patient with pulmonary Langerhans' cell histiocytosis

Eur Respir J. 2017 Oct 12;50(4):1700521. doi: 10.1183/13993003.00521-2017. Print 2017 Oct.

Authors

Li Zhang¹, Gustavo Pacheco-Rodriguez¹, Wendy K Steagall¹, Jiro Kato¹, Thomas V Colby², Mary Haughey¹, Joel Moss³

Affiliations

¹ Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
² Dept of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, AZ, USA.
³ Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA [email protected].

PMID: 29025887
DOI: 10.1183/13993003.00521-2017

No abstract available

Publication types

Letter
Research Support, N.I.H., Intramural

MeSH terms

Adult
Antigens, CD / metabolism
Antigens, CD1
Biomarkers / analysis
Female
GTP Phosphohydrolases / analysis
GTP Phosphohydrolases / genetics*
Histiocytosis, Langerhans-Cell* / blood
Histiocytosis, Langerhans-Cell* / diagnosis
Histiocytosis, Langerhans-Cell* / genetics
Humans
Langerhans Cells / immunology
Lectins, C-Type / metabolism
Lung / diagnostic imaging
Male
Mannose-Binding Lectins / metabolism
Membrane Proteins / analysis
Membrane Proteins / genetics*
Middle Aged
Mutation
Neoplastic Cells, Circulating*
Proto-Oncogene Proteins B-raf / analysis
Proto-Oncogene Proteins B-raf / genetics*
Tomography, X-Ray Computed / methods

Substances

Antigens, CD
Antigens, CD1
Biomarkers
CD1a antigen
CD207 protein, human
Lectins, C-Type
Mannose-Binding Lectins
Membrane Proteins
BRAF protein, human
Proto-Oncogene Proteins B-raf
GTP Phosphohydrolases
NRAS protein, human