DQ Wa gives rise to a DQ beta restriction fragment pattern indistinguishable from that of the DQw3.2 sub-type of DQw3

A Bushell; K J Wood; P J Morris

doi:10.1111/j.1399-0039.1988.tb01635.x

DQ Wa gives rise to a DQ beta restriction fragment pattern indistinguishable from that of the DQw3.2 sub-type of DQw3

Tissue Antigens. 1988 Jul;32(1):41-5. doi: 10.1111/j.1399-0039.1988.tb01635.x.

Authors

A Bushell¹, K J Wood, P J Morris

Affiliation

¹ Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Headington, England.

PMID: 2903583
DOI: 10.1111/j.1399-0039.1988.tb01635.x

Abstract

DQ beta restriction fragment patterns have been obtained from five DRw8 cell lines homozygous for the null DQ allele, DQWa. The enzymes Bgl II, Bam HI and Pvu II generate DQ beta patterns which are indistinguishable from those obtained from cell lines homozygous for DQw3.2.

MeSH terms

Cell Line
DNA / analysis
HLA-DQ Antigens / genetics*
HLA-DQ beta-Chains
Humans
Nucleic Acid Hybridization
Polymorphism, Genetic*
Polymorphism, Restriction Fragment Length*

Substances

HLA-DQ Antigens
HLA-DQ beta-Chains
HLA-DQ3 antigen
HLA-DQbeta antigen
HLA-DQwa antigen
DNA