[A cross-sectional study on HIV/AIDS "90-90-90" treatment target in Shandong province, 2015]

Zhonghua Liu Xing Bing Xue Za Zhi. 2017 Oct 10;38(10):1367-1371. doi: 10.3760/cma.j.issn.0254-6450.2017.10.014.
[Article in Chinese]

Abstract

Objective: To analyze the status and its factors associated with HIV/AIDS- "90-90-90" -treatment-target in Shandong province, China. Methods: Data regarding testing, treatment on HIV/AIDS in Shandong province by December 31, 2015 was collected. Chi-square test and logistic regression model were used to analyze related factors associated with the "90-90-90" -treatment-target. Results: Of the 11 700 estimated HIV/AIDS, 61.2% were diagnosed, of whom 74.4% had received Highly active antiretroviral therapy (HAART) . More than 80% of the HIV/AIDS on HAART reached the criteria on viral suppression. HIV/AIDS infected by homosexual contacts were less likely to seek for diagnosis (P<0.05). HIV/AIDS lived in Qingdao city (OR=1.30, 95%CI: 1.05-1.60), Yantai city (OR=1.53, 95%CI: 1.02-2.31) and Weihai city (OR=1.96, 95%CI: 1.07-3.58) were more likely to receive HAART. HIV/AIDS patients that infected through homosexual or (OR=0.12, 95%CI:0.06-0.24) or heterosexual contacts (OR=0.13, 95%CI: 0.07-0.26), through injecting drug use (OR=0.08,95%CI: 0.03-0.17) or being diagnosed at the custodial institutions (OR=0.29, 95%CI: 0.21-0.41) were less likely to receive HAART. HIV/AIDS patients who received HAART at medical institutions (OR=1.81, 95%CI: 1.05-3.47) were more likely to meet the level of Viral load (VL) suppression. However, those who were infected through homosexual (OR=0.43, 95%CI: 0.25-0.75) or heterosexual contacts (OR=0.49, 95%CI: 0.28-0.81) or diagnosed at the custodial institutions (OR=0.48, 95%CI: 0.28-0.80) were less likely to meet the criteria set for VL suppression. Conclusions: There was a gap between the status of testing/treatment and the target on HIV/AID "90-90-90" -treatment,especially on the target set for testing, in Shandong Province. Both HIV testing and comprehensive care services need to be strengthened.

目的: 分析山东省2015年艾滋病防治策略"三个90%"(即90%诊断、90%治疗及90%有效)"目标的进展情况及相关影响因素。 方法: 收集山东省现存活HIV感染者/AIDS患者(HIV/AIDS)检测发现、接受高效抗反转录病毒治疗(HAART)服务的相关信息,分析进展情况。采用χ(2)检验进行单因素分析,多因素logistic回归模型进行多因素分析。 结果: 2015年12月31日,山东省估计现存活HIV/AIDS有11 700例,检测发现率61.2%,HAART率74.4%,病毒载量(VL)抑制率81.8%。经同性传播的HIV/AIDS检测发现比例较低(P<0.05)。青岛市(OR=1.30,95%CI:1.05~1.60)、烟台市(OR=1.53,95%CI:1.02~2.31)和威海市(OR=1.96,95%CI:1.07~3.58)的HIV/AIDS接受HAART的比例较高;同性传播(OR=0.12,95%CI:0.06~0.24)、异性传播(OR=0.13,95%CI:0.07~0.26)、注射吸毒传播(OR=0.08,95%CI:0.03~0.17),羁押场所检测发现(OR=0.29,95%CI:0.21~0.41)的HIV/AIDS接受HAART比例较低;医疗机构接受HAART服务的HIV/AIDS(OR=1.81,95%CI:1.05~3.47)的VL抑制比例较高;同性传播(OR=0.43,95%CI:0.25~0.75)、异性传播(OR=0.49,95%CI:0.28~0.81),羁押场所检测发现(OR=0.48,95%CI:0.28~0.80)的HIV/AIDS的VL抑制比例较低。 结论: 山东省2015年现存活HIV/AIDS的检测发现率、HAART率和VL抑制率与2020年实现的艾滋病防治策略"三个90%"目标仍有一定差距,尤其是检测发现目标。需加强检测和艾滋病综合关怀服务。.

Keywords: 90-90-90 treatment target; Control and prevention strategy; HIV/AIDS; Status.

MeSH terms

  • Acquired Immunodeficiency Syndrome
  • Adult
  • Antiretroviral Therapy, Highly Active*
  • China / epidemiology
  • Cross-Sectional Studies
  • Female
  • HIV Infections / drug therapy*
  • HIV Infections / epidemiology
  • HIV Infections / virology
  • Heterosexuality
  • Homosexuality
  • Humans
  • Logistic Models
  • Male
  • Mass Screening
  • Viral Load / drug effects*