Efficacy of modified less invasive quick replacement using mild hypothermic arrest and partial retrograde cerebral perfusion for type A acute aortic dissection

Gen Thorac Cardiovasc Surg. 2018 Jan;66(1):33-37. doi: 10.1007/s11748-017-0844-3. Epub 2017 Oct 27.

Abstract

Objective: We previously reported a unique technique called "less invasive quick replacement (LIQR)" for treating type A acute aortic dissection with moderate hypothermic arrest (28 °C). This study examines the modified LIQR using mild hypothermic arrest (30 °C) with partial retrograde cerebral perfusion (RCP).

Methods: 187 patients were divided into 2 groups: group L consisted of 130 patients underwent LIQR without any cerebral perfusion; group M consisted of 57 patients who were treated with modified LIQR. In modified LIQR, circulatory arrest was commenced under the 30 °C for open distal aortic stamp fixation. RCP was used during final half anastomosis of the prosthesis and then rapid re-warming was initiated.

Results: The incidence of additional valve or coronary surgeries was significantly higher in group M (28.1%) than in group L (9.2%). The average rectal temperature was significantly higher in group M (29.5 °C) than in group L (27.4 °C). The durations of brain ischemia (M 7.7 min; L 18.6 min), cardiopulmonary bypass (M 82.0 min; L 93.3 min), and overall operation (M 145.2 min; L 154.2 min) were significantly shorter in group M. The incidence of postoperative brain damage was 6 patients (4.6%) in group L, but none in group M. The hospital mortality rate was 3 patients in group L (2.3%). All group M patients were discharged from the hospital without any complications.

Conclusion: Modified LIQR is safe and effective. It makes the surgery much quicker and is a less invasive procedure. The surgical outcome was also favorable.

Keywords: Aorta; Aortic dissection; Cardiovascular surgery.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anastomosis, Surgical
  • Aorta / surgery
  • Aortic Aneurysm, Thoracic / surgery*
  • Aortic Dissection / surgery*
  • Blood Vessel Prosthesis Implantation*
  • Brain Ischemia / etiology
  • Cardiopulmonary Bypass / methods
  • Female
  • Hospital Mortality
  • Humans
  • Hypothermia, Induced / methods*
  • Male
  • Middle Aged
  • Perfusion / adverse effects
  • Replantation
  • Treatment Outcome