Effects of Dietary n-6:n-3 PUFA Ratios on Lipid Levels and Fatty Acid Profile of Cherry Valley Ducks at 15-42 Days of Age

J Agric Food Chem. 2017 Nov 22;65(46):9995-10002. doi: 10.1021/acs.jafc.7b02918. Epub 2017 Nov 10.

Abstract

The objective of this study was to investigate the effects of dietary n-6:n-3 PUFA ratio on growth performance, serum and tissue lipid levels, fatty acid profile, and hepatic expression of fatty acid synthesis genes in ducks. A total of 3168 15-day old ducks were fed different n-6:n-3 PUFA ratios: 13:1 (control), 10:1, 8:1, 6:1, 4:1, and 2:1. The feeding trial lasted 4 weeks. Our results revealed that dietary n-6:n-3 PUFA ratios had no effects on growth performance. The 2:1 group had the highest serum triglyceride levels. Serum total cholesterol and HDL levels were higher in the 13:1 and 8:1 groups than in the 6:1 and 2:1 groups. The concentration of C18:3n-3 in serum and tissues (liver and muscle) increased with decreasing dietary n-6:n-3 PUFA ratios. The hepatic expression of FADS2, ELOVL5, FADS1, and ELOVL2 increased on a quadratic function with decreasing dietary n-6:n-3 PUFA ratios. These results demonstrate that lower dietary n-6:n-3 PUFA ratios had strong effects on the fatty acid profile of edible parts and the deposition of n-3 PUFAs in adipose tissue of ducks.

Keywords: duck; fatty acid profile; gene mRNA expression; n-6:n-3 PUFA ratio; serum lipid level.

MeSH terms

  • Animal Feed / analysis*
  • Animals
  • Ducks / growth & development*
  • Ducks / metabolism*
  • Fatty Acids / analysis
  • Fatty Acids / metabolism
  • Fatty Acids, Omega-3 / analysis
  • Fatty Acids, Omega-3 / metabolism*
  • Female
  • Lipid Metabolism
  • Liver / chemistry
  • Liver / metabolism
  • Male

Substances

  • Fatty Acids
  • Fatty Acids, Omega-3